A Serological Study of Herpes simplex Virus Type 1 Antibody over a 13-Year Period

Abstract
HSV–1 serum antibody titers determined by 50% plaque reduction and confirmed by radioimmunoassay in 11 samples from an individual over a 13-year period indicated a significant increase between the first sample and a sample taken 9 years later. This increase did not seem to reflect loss of antibody in the low titered serum sample due to storage.

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