Incubation Period of Infectious Diseases

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Abstract
The incubation period is the time interval between exposure to a disease‐causing agent and the onset of symptomatic disease. For example, the incubation period of an infectious disease refers to the time interval between infection or exposure to a viral or bacterial agent and the onset of symptomatic (clinical) disease. The incubation period is also called the clinical latency period. The focus of this article is on modeling and estimating the incubation period of infectious diseases. However, some of the ideas may also be applicable to the incubation period of noninfectious disease, for example, the incubation period of radiation‐induced cancer that refers to the time interval from radiation exposure to cancer diagnosis. Alternative designs for the estimation of an incubation period are reviewed, and methods to synthesize studies on incubation periods are mentioned.