FIBRINOLYTIC AND ANTIFIBRINOLYTIC ACTIVITY IN PREGNANCY

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Abstract
Fibrinolytic activity and serum antifibrinolysin were estimated in normal pregnant women, during and after labour.The decreased fibrinolytic activity found during labour returned to non-pregnant levels within 24 hours of delivery. During the same period, the serum antifibrinolysin was rapidly diminished.It is suggested that the post-partum increase in fibrinolytic activity to non-pregnant levels is due to alterations in the fibrinolytic system itself, as well as to changes in circulating antifibrinolysin.