The Preparation and the Antibacterial and Antifungal Properties of Some Substituted Benzyl Alcohols
- 1 December 1958
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 10 (Supplement) , 149T-159T
- https://doi.org/10.1111/j.2042-7158.1958.tb10394.x
Abstract
A number of substituted benzyl alcohols have been prepared and together with some related, commercially available, compounds have been tested for antibacterial and antifungal properties. The most active inhibitory compound was 3:4:5-trichlorobenzyl alcohol followed by 4-chloro-3:5-dimethyl-, 3:4-dichloro- and 2:4-dichlorobenzyl alcohols, but saturated aqueus solutions of the last three compounds were more rapidly bactericidal. Pharmacological tests have shown that 2:4-dichlorobenzyl alcohol has low toxicity.Keywords
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