The digital code of DNA
- 1 January 2003
- journal article
- editorial
- Published by Springer Nature in Nature
- Vol. 421 (6921) , 444-448
- https://doi.org/10.1038/nature01410
Abstract
The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: its digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information--the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behaviour of the genes.Keywords
This publication has 19 references indexed in Scilit:
- A rapid method for determining sequences in DNA by primed synthesis with DNA polymerasePublished by Elsevier ,2004
- [16] An automated DNA synthesizer employing deoxynucleoside 3′-phosphoramiditesPublished by Elsevier ,1987
- Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell AnemiaScience, 1985
- New Protein Sequenator with Increased SensitivityScience, 1980
- A new method for sequencing DNA.Proceedings of the National Academy of Sciences, 1977
- Nucleotide sequence of bacteriophage φX174 DNANature, 1977
- General Nature of the Genetic Code for ProteinsNature, 1961
- The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotidesProceedings of the National Academy of Sciences, 1961
- An Unstable Intermediate Carrying Information from Genes to Ribosomes for Protein SynthesisNature, 1961
- Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic AcidNature, 1953