Hepatic δ‐Aminolaevulinic Acid Synthetase Activity in Symptomatic Porphyria
- 1 August 1968
- journal article
- Published by Wiley in British Journal of Haematology
- Vol. 15 (2) , 123-130
- https://doi.org/10.1111/j.1365-2141.1968.tb01521.x
Abstract
Hepatic ALA synthetase activity was determined on biopsy material from 12 patients with symptomatic porphyria. Five patients had values at least 1.5 times greater than the highest normal value whilst the remaining seven had values within or slightly above the highest normal value. No correlation was observed between ALA synthetase activity and urinary or stool porphyrin excretion. The metabolic significance of this finding is discussed.Keywords
This publication has 14 references indexed in Scilit:
- EFFECT OF CHLOROQUINE ON HEPATIC UROPORPHYRIN METABOLISM IN PATIENTS WITH PORPHYRIA CUTANEA TARDA1,2Medicine, 1966
- Stilbestrol-Induced Porphyria: Increase in Hepatic δ-Aminolevulinic Acid SynthetaseBlood, 1966
- Fumarate Reductase in the Control of Heme BiosynthesisScience, 1966
- The determination of aminoketones in biological fluidsAnalytical Biochemistry, 1966
- The role of succinyl-CoA synthetase in the control of heme biosynthesisBiochimica et Biophysica Acta (BBA) - General Subjects, 1965
- Control of hemoglobin synthesis in the cultured chick blastoderm by delta-aminolevulinic acid synthetase: increase in the rate of hemoglobin formation with delta-aminolevulinic acid.Proceedings of the National Academy of Sciences, 1965
- ACUTE INTERMITTENT PORPHYRIA: THE FIRST “OVERPRODUCTION DISEASE” LOCALIZED TO A SPECIFIC ENZYMEProceedings of the National Academy of Sciences, 1965
- A New Digestion Reagent for the Determination of Microgram Quantities of Phosphorus in Organic Compounds.Analytical Chemistry, 1964
- Studies on the Mechanism of the Inhibition of Galactose Oxidation by EthanolJournal of Biological Chemistry, 1961
- Allgemeinsymptome der späten Hautporphyrie (Porphyria cutanea tarda) als Hinweise für deren BehandlungDeutsche Medizinische Wochenschrift (1946), 1961