Adaptive predictive control of a multistage fermentation process

Abstract
This paper reports on the application of adaptive control techniques to the control of real-life biotechnological processes. The problem of regulation of the substrate concentration in the effluent of a multistage fermentation plant is considered in view of recent adaptive control concepts. The direct use of the process non-linear dynamics together with the on-line estimation of key process parameters gives rise to a robust (as BIBO stability analysis suggests) and efficient (as simulation and experimental results indicate) control scheme.