Growth, Behavior, and Brain Catecholamines in Lead-Exposed Neonatal Rats: A Reappraisal
- 31 January 1975
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 187 (4174) , 359-361
- https://doi.org/10.1126/science.1167426
Abstract
Daily oral administration of lead to newborn rats has no adverse effect on their body growth. Lead-treated rats were more active than age-matched controls. Endogenous levels of brain dopamine were unchanged, whereas norepinephrine was increased, suggesting a possible relationship between lead exposure during earliest developmental periods, increased motor activity, and brain norepinephrine, and not brain dopamine as previously postulated.Keywords
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