STUDIES ON PERMEABILITY OF THE LEUCOCYTE

Publisher Website
Google Scholar
Abstract
Leukocytes from normal donors were separated from peripheral blood and planted in 7 tissue culture vials containing media of 7 different tonicities; 3 hypotonic, 3 hypertonic, and 1 isotonic. Quantitative studies were made on the permeability rates of leukocytes to water, as reflected in their resistance to anisotonia over stated time intervals. It was found that lysis of lymphocytes in terms of reduction in absolute numbers, occurred least often in hypotonia of 237 milliosmoles; Lysis of polymorphonuelear neutrophiles, in terms of reduction in absolute numbers occurred least often in isotonia and slight hyper -tonia, of 320-340 milliosmoles. No explanation is offered for the preferential survival of polymorphonuclear neutrophiles in hypertonia and lymphocytes in hypotonia.

This publication has 10 references indexed in Scilit: