A Tissue Culture Color Test for Measuring Influenza Virus and Antibody.

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Abstract
A tissue culture color test has been developed for titration of influenza virus and antibody using secondary monkey kidney cell cultures. Virus titrations with the color test are comparable in accuracy with those done in roller tube cultures, mean titer being 0.56 logs lower in the color test. Antibody content of immune sera (animal or human) can readily be determined and slopes of neutralization curves determined by color test are comparable to those found in ovo. Color test neutralization titers and hemagglutination-inhibition titers of the same sera show a significant association.