FUNCTIONAL-HETEROGENEITY OF MACROPHAGES
- 1 January 1979
- journal article
- research article
- Vol. 36 (4) , 729-732
Abstract
The antibody[Ab]-binding activities of rabbit peritoneal macrophages separated on discontinuous gradients of Ficoll were investigated. The Ab was rabbit anti-ovalbumin Ig[immunoglobulin]G labeled with 125I. Of the 5 fractions obtained, 1 macrophage fraction bound substantially more Ab than the others. These macrophages possessed more Fc receptor sites than the others and the number of Fc receptors (n) and the association constant (K) of these cells was calculated. By EM, the phagocytic activity of the subpopulation with most Fc receptors was less than that of the others.This publication has 11 references indexed in Scilit:
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