Reference values for peak flow and FEV1variation in healthy schoolchildren using home spirometry
- 16 April 2008
- journal article
- Published by European Respiratory Society (ERS) in European Respiratory Journal
- Vol. 32 (5) , 1262-1268
- https://doi.org/10.1183/09031936.00148107
Abstract
Current reference values for diurnal peak flow variation in healthy children (median 8.2%; 95th percentile 31%) are so high that considerable overlap exists with those of asthmatic children. These values have been obtained using written peak flow diaries, which are unreliable. The aim of the present study was to obtain reliable reference values for the variation in peak flow and forced expiratory volume in one second (FEV1) in healthy schoolchildren using home spirometry with electronic data storage.Healthy schoolchildren (n = 204; 100 males) aged 6–16 yrs measured their peak flow and FEV1twice daily for 2 weeks using an electronic home spirometer. The variation in peak flow and FEV1were calculated as a diurnal amplitude as a percentage of the day’s mean.The mean peak flow variation was 6.2% (95th percentile 12.3%) and the mean FEV1variation was 5.7% (95th percentile 11.8%).Using home spirometry with electronic data storage, healthy schoolchildren show considerably less peak flow and forced expiratory volume in one second variation than previously reported on the basis of written peak flow diaries. Being the 95th percentiles of the distributions in healthy children, a peak flow variation of 12.3% and an forced expiratory volume in one second variation of 11.8% are suggested as cut-off values for disease when using home spirometry.Keywords
This publication has 27 references indexed in Scilit:
- Evaluation of daily home spirometry for school children with asthma: New insightsPediatric Pulmonology, 2006
- Exhaled nitric oxide in healthy nonatopic school‐age children: Determinants and height‐adjusted reference valuesPediatric Pulmonology, 2006
- Applicability of interrupter resistance measurements using the MicroRint® in daily practiceRespiratory Medicine, 2003
- Assessment of a low-cost home monitoring spirometer for childrenPediatric Pulmonology, 2002
- Spirometry in children aged 3 to 5 years: Reliability of forced expiratory maneuvers*Pediatric Pulmonology, 2001
- Specific airway resistance, interrupter resistance, and respiratory impedance in healthy children aged 2–7 yearsPediatric Pulmonology, 1998
- Assessment of accuracy and applicability of a portable electronic diary card spirometer for asthma treatmentRespiratory Medicine, 1996
- Short-term compliance with peak flow monitoring: Results from a study of inner city children with asthmaPediatric Pulmonology, 1996
- Growth and other factors affecting peak expiratory flow rate.Archives of Disease in Childhood, 1989
- Standardization of lung function testing in children: Proceedings and recommendations of the GAP conference Committee, cystic fibrosis foundationThe Journal of Pediatrics, 1980