STUDIES ON THE FORMATION OF TOBACCO MOSAIC VIRUS RIBONUCLEIC ACID, II. DEGRADATION OF HOST RIBONUCLEIC ACID FOLLOWING INFECTION

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Abstract
The micro-somal RNA present in the cytoplasmic function of the tobacco leaf forms about 55-60% of the total leaf RNA. Its purine and pyrimidine composition is similar to that of the total RNA of the leaf. It is characterized by a high guanylic acid and belongs to the GC-type. Its composition is markedly different from that of TMV-RNA which belongs to the AU-type. Following infection with TMV, the microsomal RNA is rapidly degraded and its degradation products are utilized in the synthesis of TMV-RNA. The amount of TMV-RNA synthesized is approximately equal to the amount of microsomal RNA degraded.