Attenuation of a -Adrenergic Response in Rats Treated Chronically with Ethynyl Estradiol

Abstract
Chronic treatment of ovariectomized female rats with ethynyl estradiol (30 and 72 .mu.g/kg per day) attenuated the increase in tail skin temperature characteristically accompanying s.c. administration of l-isoproterenol (50, 100 or 200 .mu.g/kg).