OBSERVATIONS CONCERNING THE CHOLATE: CHOLESTEROL RELATIONSHIP IN CLINICAL AND EXPERIMENTAL NEPHROSIS 12
Open Access
- 1 February 1953
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 32 (2) , 121-124
- https://doi.org/10.1172/jci102719
Abstract
An excess accumulation of bile acid (hypercholatemia) is found in the blood of human subjects with nephrosis and in the blood of rats in which exptl. nephrosis has been induced by injn. of anti-rat kidney serum, whenever hypercholesteremia also is present. The nephrotic rat also exhibits diminished ability to rid his blood of excess injected cholate. The feeding of cholate to nephrotic rats appeared to prevent the decrease of plasma cholesterol, which usually occurred, following its initial maximal rise.Keywords
This publication has 9 references indexed in Scilit:
- The Accumulation of Serum Cholate and its Relationship to HypercholesteremiaScience, 1952
- Production and Excretion of Cholesterol in MammalsAmerican Journal of Physiology-Legacy Content, 1952
- REVIEW - ON THE REGULATION OF BLOOD CHOLESTEROL1952
- Effect of Various Bile Acids on the Hypercholesteremia Following Biliary Obstruction in the RatAmerican Journal of Physiology-Legacy Content, 1951
- Cholic Acid: An Adequate Stimulus for Hypercholesteremia in the Normal Fasting Rat.Experimental Biology and Medicine, 1951
- Bile Acid Content of Rat Bile and of Normal and Icteric Rat PlasmaAmerican Journal of Physiology-Legacy Content, 1951
- NEPHROTIC SYNDROME IN RATS1951
- OBSERVATIONS CONCERNING THE PRODUCTION AND EXCRETION OF CHOLESTEROL IN MAMMALS .1. PLASMA CHOLESTEROL AFTER BILE DUCT LIGATION AND FREE CHOLESTEROL INJECTION1950
- INFLUENCE OF ADRENAL CORTICAL STEROIDS UPON THE BLOOD PRESSURE AND THE RATE OF PROGRESSION OF EXPERIMENTAL NEPHRITIS IN RATSEndocrinology, 1946