Antimalarial artemisinin analogs. Synthesis via chemoselective CC bond formation and preliminary biological evaluation
Open Access
- 1 March 1999
- journal article
- Published by Elsevier in Tetrahedron
- Vol. 55 (12) , 3625-3636
- https://doi.org/10.1016/s0040-4020(98)01170-3
Abstract
No abstract availableThis publication has 25 references indexed in Scilit:
- Synthesis and in vivo antimatarial activity of 12α-trifluoromethyl-hydroartemisininBioorganic & Medicinal Chemistry Letters, 1996
- Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapyMicrobiological Reviews, 1996
- Deuterated antimalarials: Synthesis of trideutero-artemisinin, dihydroartemisinin, and arteetherJournal of Labelled Compounds and Radiopharmaceuticals, 1996
- Antimalarial Activity of Artemisinin (Qinghaosu) and Related Trioxanes: Mechanism (s) of ActionPublished by Elsevier ,1996
- Replacement of the nonperoxidic trioxane oxygen atom of artemisinin by carbon: Total synthesis of (+)-13-carbaartemisinin and related structuresTetrahedron Letters, 1995
- Synthesis and Antimalarial Activities of 12.beta.-Allyldeoxoartemisinin and Its DerivativesJournal of Medicinal Chemistry, 1995
- Amplified asymmetric dihydroxylation of a racemic cyclopenteneJournal of the Chemical Society, Chemical Communications, 1995
- Total Synthesis of the Antimalarial Sesquiterpene Peroxide Qinghaosu and Yingzhaosu AAccounts of Chemical Research, 1994
- Extraordinarily potent antimalarial compounds: new, structurally simple, easily synthesized, tricyclic 1,2,4-trioxanes.Journal of Medicinal Chemistry, 1992
- A short and stereospecific synthesis of (+)-deoxoartemisinin and (−)-deoxodesoxyartemisininTetrahedron Letters, 1989