Solution structure of μ‐conotoxin GIIIA analysed by 2D‐NMR and distance geometry calculations
- 28 January 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 278 (2) , 160-166
- https://doi.org/10.1016/0014-5793(91)80107-e
Abstract
We have investigated the structure of μ-conotoxin GIIIA by 2D-NMR methods. The assignment of 1H NMR spectra and a quantitative analysis of NOE and J-coupling data are presented. These results were used for the calculation of secondary structure elements of μ-conotoxin GIIIA. Distance geometry calculations were carried out to define the global folding of the peptide.Keywords
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