Hereditary Angioneurotic Edema (HANE): Lack of Close Linkage between HLA Haplotypes and C1 Esterase Inhibitor Deficiency
- 1 February 1977
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 9 (2) , 90-95
- https://doi.org/10.1111/j.1399-0039.1977.tb01087.x
Abstract
The HL-A haplotypes were defined in a series including 11 patients with HANE, 5 symptom-free subjects with pathological laboratory findings characteristic of HANE and their 33 healthy kinsmen. The subjects belonged to 2 Finnish families representing the more common form of HANE which is recognized by the immunochemically observed decrease of the inhibitor (C1-1NH) blocking the esterase activity of the 1st complement component. No linkage between HANE and the HL-A system was found.This publication has 14 references indexed in Scilit:
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