Purification of Propionin, an Antiviral Agent from Propionibacteria

Abstract
Summary A potent antiviral agent, pro-pionin, active against Col. SK virus infections in mice, has been isolated from cellular extracts of Propionibacterium freudenreichii. Partial purification of propionin by organic solvents, Sephadex and paper chroma tography has been achieved. Preliminary identification has been carried out and the available data indicate propionin to be peptide in nature.