The Quantitation of Triazolam in Postmortem Blood by Gas Chromatography/Negative Ion Chemical Ionization Mass Spectrometry*
- 1 November 1986
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 10 (6) , 241-244
- https://doi.org/10.1093/jat/10.6.241
Abstract
A specific and sensitive assay has been developed to quantitate triazolam in postmortem blood using 2H6-triazolam as an internal standard. Triazolam is isolated from whole blood by adsorption on an Amberlite® XAD-2 resin and subsequent elution with an organic solvent. The extract is analyzed by gas chromatography/mass spectometry using selected ion monitoring (GC/MS/SIM) in the negative chemical ionization mode (CI−). The procedure is presently being used in case work and the results from 36 cases are presented.This publication has 6 references indexed in Scilit:
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