Methamphetamine-Induced Insulin Release
- 1 October 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 174 (4004) , 66-68
- https://doi.org/10.1126/science.174.4004.66
Abstract
Administration of methamphetamine or amphetamine to rats and mice produces a rapid increase in the level of immunoassayable plasma insulin not attributable to hyperglycemia. While in the mouse this release of insulin is followed consistently by a profound hypoglycemia, in the rat this response is variable. Studies in vitro demonstrate that insulin is released by a direct effect of methamphetamine on the pancreas.Keywords
This publication has 4 references indexed in Scilit:
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- Tranylcypromine: A Potent Insulin Secretagogue and Hypoglycemic AgentDiabetes, 1968
- A Radioimmunological Assay Method for Insulin Using Insulin-125I and Gel FiltrationJournal of Clinical Endocrinology & Metabolism, 1965
- Effects of d-amphetamine on blood glucose and tissue glycogen levels of isolated and aggregated miceBiochemical Pharmacology, 1965