Optimization of Lyophilization Conditions for Recombinant Human Interleukin-2 by Dried-State Conformational Analysis Using Fourier-Transform Infrared Spectroscopy
- 1 January 1995
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 12 (9) , 1250-1259
- https://doi.org/10.1023/a:1016296801447
Abstract
Purpose. Examination of the dried-state conformation of interleukin-2 (IL-2) was used to determine the pH conditions and stabilizers that provide optimal storage stability for the lyophilized product.Keywords
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