LONG-TERM SURVIVAL OF NORMAL ADULT HUMAN-TISSUES AS XENOGRAFTS IN CONGENITALLY ATHYMIC NUDE-MICE
- 1 January 1981
- journal article
- research article
- Vol. 66 (5) , 849-858
Abstract
Bronchi, pancreatic ducts and colons from adult humans were maintained as xenografts in congenitally athymic nude N:NIH(S) mice for 715, 145 and 89 days, respectively. After an ischemic crisis and revascularization of the human tissue, the epithelium regenerated to a normal differentiated morphology. The long-term survival of normal adult human epithelial tissues as xenografts provides model systems for the study of the interactions of chemical and/or physical carcinogens with human tissues.This publication has 7 references indexed in Scilit:
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