Targeted Inactivation of Mdm2 RING Finger E3 Ubiquitin Ligase Activity in the Mouse Reveals Mechanistic Insights into p53 Regulation

This publication has 36 references indexed in Scilit:

• Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo
  Proceedings of the National Academy of Sciences, 2006
• Temporal dissection of p53 function in vitro and in vivo
  Nature Genetics, 2005
• Tumor Suppressor ARF Degrades B23, a Nucleolar Protein Involved in Ribosome Biogenesis and Cell Proliferation
  Molecular Cell, 2003
• The MDM2 RING-finger domain is required to promote p53 nuclear export
  Nature Cell Biology, 2000
• Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase
  Oncogene, 2000
• MdmX Protects p53 from Mdm2-Mediated Degradation
  Molecular and Cellular Biology, 2000
• p300/MDM2 Complexes Participate in MDM2-Mediated p53 Degradation
  Molecular Cell, 1998
• Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
  Published by Wiley ,1998
• Mdm2 promotes the rapid degradation of p53
  Nature, 1997
• Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
  Nature, 1995