Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells

Abstract
Rat cells transformed by the highly oncogenic adenovirus type 12 lack at least 2 cellular proteins which are present in cells transformed by the nononcogenic adenovirus type 5 and in untransformed cells. One protein has been identified as the H chain of the rat class I major histocompatibility complex. This finding may explain the difference in oncogenicity between adenoviral species.