Morphologic Phenotyping with MR Microscopy: The Visible Mouse
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- 1 March 2002
- journal article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 222 (3) , 789-793
- https://doi.org/10.1148/radiol.2223010531
Abstract
A method for rapid morphologic phenotyping is demonstrated by using magnetic resonance microscopy. Whole fixed C57BL/6J mice were imaged at 110-microm isotropic resolution; limited volumes of the intact specimen, at 50-microm isotropic resolution; and isolated organs, at 25-microm isotropic resolution. The three-dimensional imaging technique was applied to uricase knockout mice to demonstrate the method for the evaluation of morphologic phenotype.Keywords
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