The Effect of Epinephrine, Insulin, and Hyperthyroidism on the Rapid Intravenous Glucose Tolerance Test1

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Abstract
The rate of disappearance of glucose, which is that of a monomolecular reaction, was detd. in 17 normal men with and without epinephrine, insulin, and hyperthyroidism. The disappearance rate of glucose was decreased after admn. of epinephrine and increased after insulin. In 15 of 17 subjects with hyperthyroidism, the rate of glucose disappearance was normal or increased. After remission of the hyperthyroidism the rate of disappearance of glucose was slower in 8, unchanged in 5, and slightly more rapid in 2 patients. There was no correlation in the hyperthyroid group between the glucose disappearance rate and the oral glucose tolerance test before or after treatment.