Preoperative Antibiotic Prophylaxis

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Abstract
POSTOPERATIVE wound infections affect at least 920,000 of the 23 million patients who undergo surgery each year in the United States.1 The rates of infection vary according to the procedure: less than 3 infections per 100 for clean procedures (i.e., those in which there is no violation of aseptic technique and the alimentary, respiratory, and genitourinary systems are not entered), up to 4 per 100 for clean—contaminated procedures (i.e., those in which these systems are entered but without spillage), and up to 9 per 100 for grossly contaminated procedures. For specific operations, such as cholecystectomy, the rate may be five . . .