Double translocation t(7;12),t(2;6) heterozygosity in one family
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 40 (2) , 135-147
- https://doi.org/10.1007/bf00272294
Abstract
Double translocation heterozygosity t(2;6),t(7;12) in three generations of a Dutch family is described: the segregation of a double translocation in more than one generation has not been previously published. The index case was a 16-year-old mentally retarded boy with partial trisomy 12p who showed several dysmorphic features such as high prominent forehead, flat face, flat and short nose bridge, short nose, dysplastic ears, prominent lower lip, and several skeletal abnormalities. Based on the findings in this patient and those in nine other cases, the existence of a specific trisomy 12p syndrome is postulated.This publication has 19 references indexed in Scilit:
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