Structure of Pna-Nucleic Acid Complexes
- 1 May 1997
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 16 (5-6) , 617-621
- https://doi.org/10.1080/07328319708002925
Abstract
The solution structure of the PNA-DNA hybrid H-GCTATGTC-NH2d(GACATAGC), determined by NMR methods, shows a new conformation which has elements of both A- and B-form DNA. Comparison with other PNA-nucleic acid complexes points to common structural features, but also demonstrates the ability of PNA to conform to nucleic acid partners of different conformations.Keywords
This publication has 11 references indexed in Scilit:
- Solution structure of a peptide nucleic acid–DNA duplexNature Structural & Molecular Biology, 1996
- Peptide Nucleic Acids (PNA): Synthesis, properties and potential applicationsBioorganic & Medicinal Chemistry, 1996
- A Nucleic Acid Triple Helix Formed by a Peptide Nucleic Acid-DNA ComplexScience, 1995
- DNA Triplexes: Solution Structures, Hydration Sites, Energetics, Interactions, and FunctionBiochemistry, 1994
- Stability of peptide nucleic acids in human serum and cellular extractsBiochemical Pharmacology, 1994
- NMR Solution Structure of a Peptide Nucleic Acid Complexed with RNAScience, 1994
- Structural Characterization of PNA-DNA Duplexes by NMR. Evidence for DNA in a B-like ConformationBiochemistry, 1994
- DNA-like double helix formed by peptide nucleic acidNature, 1994
- PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rulesNature, 1993
- Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted PolyamideScience, 1991