A comprehensive method for determining hydrophobicity constants by reversed-phase high-performance liquid chromatography
- 1 October 1988
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 31 (10) , 1923-1933
- https://doi.org/10.1021/jm00118a010
Abstract
Note: In lieu of an abstract, this is the article's first page.Keywords
This publication has 11 references indexed in Scilit:
- Comparison of phenyl- and octadecyl-modified silica gel as stationary phase for the prediction of n-octanol-water partition coefficients by high-performance liquid chromatographyJournal of Chromatography A, 1985
- Accurate, Wide-Range, Automated, High-Performance Liquid Chromatographic Method for the Estimation of Octanol/ Water Partition Coefficients II: Equilibrium in Partition Coefficient Measurements, Additivity of Substituent Constants, and Correlation of Biological DataJournal of Pharmaceutical Sciences, 1984
- Reversed-Phase Chromatographic System as a Model for Characterizing the Offset Rate of Action of Azidomorphines in Guinea-Pig IleumJournal of Liquid Chromatography, 1984
- Evaluation of a Simple HPLC Correlation Method for the Estimation of the Octanol-Water Partition Coefficients of Organic CompoundsJournal of Liquid Chromatography, 1984
- A simplified high-pressure liquid chromatography method for determining lipophilicity for structure-activity relationshipsJournal of Medicinal Chemistry, 1983
- Quantitative structure—activity relationships for herbicidesJournal of Chromatography A, 1983
- Determination of partition coefficients of very hydrophobic compounds by high-performance liquid chromatography on glyceryl-coated controlled-pore glassJournal of Chromatography A, 1982
- Simple Procedure for Determining Octanol–Aqueous Partition, Distribution, and Ionization Coefficients by Reversed-Phase High-Pressure Liquid ChromatographyJournal of Pharmaceutical Sciences, 1978
- Direct measurement of octanol-water partition coefficients by high-pressure liquid chromatographyJournal of Medicinal Chemistry, 1976
- The linear free-energy relation between partition coefficients and the binding, and conformational perturbation of macromolecules by small organic compoundsBiochemistry, 1968