TIMOLOL MALEATE IN TREATMENT OF OPEN ANGLE GLAUCOMA

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Abstract
The effect of timolol maleate on the intraocular pressure in open angle glaucoma was studied in 37 patients, of these simple glaucoma in 26 (48 eyes), capsular glaucoma in 9 (14 eyes) and chronic secondary glaucoma in 2 patients (2 eyes). These cases constituted a group which was relatively difficult to manage. The average pressure reduction caused by timolol maleate alone was .apprxeq. 23%. In 18 patients intraocular pressure was adequately controlled on timolol as the only drug and in 10 on additional drug therapy. Drug treatment failed in 5 patients; the remaining 4 failed on 1 eye while the other eye was regulated. Tonography indicates that the effect is caused by a reduction of the aqueous humour production. Side effects of locally applied timolol maleate were not seen. This drug may be the drug of choice in many instances.

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