A controlled trial for evaluating two live attenuated mumps‐measles vaccines (Urabe Am 9‐Schwarz and Jeryl Lynn‐Moraten) in young children

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Abstract
A prospective, randomised clinical trial was conducted to evaluate the efficacy of two live attenuated mumps‐measles vaccines, the Urabe Am 9‐Schwarz and the Jeryl Lynn‐Moraten vaccine, in 400 young children aged 9 months‐4.5 years (median 13.4 months). Antibody responses to both vaccine components were measured by the enzyme‐linked immunosorbent assay (ELISA); 96.9% of the seronegative children who received the Urabe Am 9‐Schwarz vaccine showed satisfactory mumps antibody responses compared to 90% of the Jeryl Lynn‐Moraten vaccine recipients (P < .01). Similar proportions of both groups, 98.5% and 96.8%, respectively, developed measles virus specific antibodies. Both vaccines were equally well tolerated and clinically acceptable.