Antibody response after application of a new live attenuated mumps vaccine (Pariorix®) measured by enzyme‐linked immunosorbent assay (ELISA)

Publisher Website
Google Scholar
Abstract
Mumps virus specific antibody concentrations were determined by enzyme‐linked immunosorbent assay (ELISA), hemolysis‐in‐gel (HIG) test, and hemagglutination‐inhibition (HI) test in 17 adult volunteers before and after vaccination with a new live mumps vaccine, Pariorix®. The results of the present study indicate that the strain Urabe‐Am 9 of the mumps virus (Pariorix) induces antibodies in 100% of seronegative adults when measured by ELISA and in 70.6% and 64.7% in HIG and HI, respectively. ELISA is therefore a very sensitive and reliable method for the demonstration of sero‐conversion after vaccination. The vaccine was well tolerated and clinically acceptable in the group of adult volunteers.

This publication has 15 references indexed in Scilit: