The Stereoselective Aldol Condensation of α-Fluoroacetates
- 1 March 1989
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 19 (5-6) , 1081-1090
- https://doi.org/10.1080/00397918908051031
Abstract
2,6-Di-t-butyl-4-methylphenyl(BHT) and benzyl α-fluoroacetates were converted to their lithium enolates and were utilized in the aldol condensation. The improved diastereoselectivity found with the BHT esters is thought to arise from of equilibration of the aldol product rather than stereoselective enolate formation.Keywords
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