Functionally homologous cell cycle control genes in budding and fission yeast
- 1 December 1982
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 300 (5894) , 706-709
- https://doi.org/10.1038/300706a0
Abstract
The cdc 2 (previously called wee 2) cell cycle start gene of Schizosaccharomyces pombe, which is required for start and the control of mitosis, was isolated from an S. pombe gene bank by complementation of a cdc 2 mutation. A functionally homologous sequence which complements the cdc 2 mutation was also isolated from a Saccharomyces cerevisiae gene bank and this sequence contains the cdc 28 cell cycle start gene of S. cerevisiae. The cdc 2 and cdc 28 genes perform homologous cell cycle control functions in the 2 organisms.Keywords
This publication has 27 references indexed in Scilit:
- A bifunctional gene product involved in two phases of the yeast cell cycleNature, 1982
- The role of protein phosphorylation in neural and hormonal control of cellular activityNature, 1982
- Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeastNature, 1981
- High-frequency transformation of the fission yeast Schizosaccharomyces pombeNature, 1981
- Isolation of genes by complementation in yeast: molecular cloning of a cell-cycle gene.Proceedings of the National Academy of Sciences, 1980
- Cell division from a genetic perspectiveThe Journal of cell biology, 1978
- Regulation of mating in the cell cycle of Saccharomyces cerevisiae.The Journal of cell biology, 1977
- Coordination of growth with cell division in the yeastExperimental Cell Research, 1977
- Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombeMolecular Genetics and Genomics, 1976
- Reversible arrest of haploid yeast cells at the initiation of DNA synthesis by a diffusible sex factorExperimental Cell Research, 1973