A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1
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- 1 February 2000
- journal article
- research article
- Published by Elsevier in Molecular Cell
- Vol. 5 (2) , 197-206
- https://doi.org/10.1016/s1097-2765(00)80416-5
Abstract
No abstract availableKeywords
This publication has 53 references indexed in Scilit:
- Calcium Depletion Dissociates and Activates Heterodimeric Notch ReceptorsMolecular and Cellular Biology, 2000
- Cell Surface Presenilin-1 Participates in the γ-Secretase-like Proteolysis of NotchJournal of Biological Chemistry, 1999
- Presenilins, Processing of β-Amyloid Precursor Protein, and Notch SignalingNeuron, 1999
- Peptidomimetic Probes and Molecular Modeling Suggest That Alzheimer's γ-Secretase Is an Intramembrane-Cleaving Aspartyl ProteaseBiochemistry, 1999
- An Essential Role for Ectodomain Shedding in Mammalian DevelopmentScience, 1998
- KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila NeurogenesisScience, 1996
- Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis.Genes & Development, 1996
- Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.The Journal of Experimental Medicine, 1996
- Signalling downstream of activated mammalian NotchNature, 1995
- Jagged: A mammalian ligand that activates notch1Cell, 1995