Development of Caco-2 Cells Expressing High Levels of cDNA-Derived Cytochrome P4503A4
- 1 January 1996
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 13 (11) , 1635-1641
- https://doi.org/10.1023/a:1016428304366
Abstract
Purpose. To develop Caco-2 cell derivatives expressing high levels of human cytochrome P450 drug metabolizing enzymes. Methods. The cDNAs for two cytochrome P450 forms, CYP2A6 and CYP3A4, were...Keywords
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