Adenosine Triphosphatase Associated with Adenosine Triphosphate-Dependent Deoxyribonuclease
- 1 January 1972
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 69 (1) , 15-19
- https://doi.org/10.1073/pnas.69.1.15
Abstract
An ATPase activity that is completely dependent on DNA is associated with the ATP-dependent DNase ( recB-recC enzyme) purified from Escherichia coli . There is a strong correlation between the ATPase and the DNase activities under various assay conditions. With E. coli DNA as substrate, 8-9 molecules of ATP are hydrolyzed to ADP and inorganic phosphate for every phosphodiester bond hydrolyzed by the DNase. The possible functional relationship of the ATPase and DNase activities is discussed.Keywords
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