Histopathologic Findings in Surgical Specimens of Endolymphatic Sac in Meniere'S Disease

Abstract
Two types of abnormality in the endolymphatic sac [human] acquired at shunt surgery were presented. One was deep brown pigmentation in the subepithelial connective tissue. The pigment did not react to Prussian blue, thus ruling out hemosiderin. The other, in 7 of 8 specimens, was perisaccular fibrosis. The fibrotic foci in 4 cases were assumed, from the findings under ordinary illumination and polarized light microscopy, to be reorganized scar tissue.