THYROID AND PARATHYROID HORMONE EFFECTS ON CALCIUM AND PHOSPHORUS METABOLISM

Abstract
The adm. of thyroid hormone to normal dogs produced a marked increase in Ca excretion, with no change in serum Ca levels and no significant changes in P metabolism. Parathyroid hormone adm. to hyperthyroid dogs produced the classical response characteristic of normal dogs. The feeding of thyroid hormone to thyroparathyroidectomized dogs produced only slight increase in urinary Ca and did not prevent serum Ca from falling to a subnormal level. There was no manifest effect on P metabolism. Serum phosphatase remained unchanged throughout. The implications of these facts are discussed.

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