EFFECT OF ANDROGENISATION ON ADENOHYPOPHYSIAL PROLACTIN CONTENT IN RATS

1 April 1967

journal article
research article
Published by Oxford University Press (OUP) in Acta Endocrinologica

Vol. 54 (4) , 663-667
https://doi.org/10.1530/acta.0.0540663

Abstract

The adenohypophyses of androgenised female rats contain significantly less prolactin than control animals. Testosterone phenylpropionate administered in the early postnatal period does not markedly change the adenohypophysial prolactin content of male rats. Since examination of the mammary gland provide no evidence of increased prolactin secretion, the decrease in the adenohypophysial prolactin content of androgenised female rats must be explained by reduced hormone production. It is suggested that androgenisation in female rats influences prolactin production by an action on the hypothalamus.

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