Multiple signaling pathways promote B lymphocyte stimulator–dependent B-cell growth and survival
Open Access
- 15 January 2008
- journal article
- Published by American Society of Hematology in Blood
- Vol. 111 (2) , 750-760
- https://doi.org/10.1182/blood-2007-03-077222
Abstract
We investigated the mechanism by which B lymphocyte stimulator (BLyS)/BAFF, a tumor necrosis factor superfamily ligand, promotes B-cell survival and resistanceKeywords
This publication has 96 references indexed in Scilit:
- BAFF and MyD88 signals promote a lupuslike disease independent of T cellsThe Journal of Experimental Medicine, 2007
- Serine 64 Phosphorylation Enhances the Antiapoptotic Function of Mcl-1Journal of Biological Chemistry, 2007
- Cytokine Stimulation Promotes Glucose Uptake via Phosphatidylinositol-3 Kinase/Akt Regulation of Glut1 Activity and TraffickingMolecular Biology of the Cell, 2007
- Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AMLBlood, 2006
- BAFF controls B cell metabolic fitness through a PKCβ- and Akt-dependent mechanismThe Journal of Experimental Medicine, 2006
- The Protein Kinase Cδ Catalytic Fragment Targets Mcl-1 for Degradation to Trigger ApoptosisJournal of Biological Chemistry, 2006
- Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune diseaseProceedings of the National Academy of Sciences, 2005
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR ComplexScience, 2005
- PI3-Kinase Regulates Survival of Chronic Lymphocytic Leukemia B-Cells by Preventing Caspase 8 ActivationLeukemia & Lymphoma, 2004
- Downregulation of Bim, a Proapoptotic Relative of Bcl-2, Is a Pivotal Step in Cytokine-Initiated Survival Signaling in Murine Hematopoietic ProgenitorsMolecular and Cellular Biology, 2001