Induction of Sister Chromatid Exchanges (SCE) inG0Lymphocytes by Plutonium-238 α-particles
- 1 January 1988
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 53 (6) , 909-915
- https://doi.org/10.1080/09553008814551271
Abstract
Irradiation of human G0 lymphocytes with plutonium-238 α-particles and X-rays was performed to investigate the production of sister chromatid exchanges (SCE). Alpha-particles produce a significant increase in SCE and this elevation is more significant when separated lymphocytes are irradiated. X-ray irradiation did not induce any significant increase in SCE. Therefore the relative biological effectiveness (RBE) for the induction of SCE by α-particles in this system is undefined and effectively infinite.This publication has 10 references indexed in Scilit:
- Production of sister-chromatid exchange by irradiation during the G1 stage: The probable role of 5-bromodeoxyuridineMutation Research Letters, 1987
- X-ray-induced SCEs and chromosomal aberrations in CHO cells: Influence of nitrogen and air during irradiation in different stages of the cell cycleMutation Research Letters, 1983
- SCEs induced by ionizing radiation are not the result of exchanges between homologous chromosomesMutation Research Letters, 1983
- The Mutagenicity of α Particles from Plutonium-238Radiation Research, 1982
- The Induction of Chromosome Aberrations in Human Lymphocytes by Alpha-radiationInternational Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1980
- X irradiation and sister chromatid exchange in cultured human lymphocytesEnvironmental Mutagenesis, 1980
- Effectiveness of 0·3 keV Carbon Ultrasoft X-rays for the Inactivation and Mutation of Cultured Mammalian CellsInternational Journal of Radiation Biology, 1979
- Cytological detection of mutagen–carcinogen exposure by sister chromatid exchangeNature, 1975
- New Giemsa method for the differential staining of sister chromatidsNature, 1974