Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots

Abstract
Endothelium-presented chemokines are critical for the entry of lymphocytes into tissues. Alon and colleagues show that transendothelial migration, but not adhesion, of effector lymphocytes on inflamed endothelium is dependent on chemokine signals.