NS 257 (1,2,3,6,7,8-hexahydro-3(hydroxyimino)-N,N,7-trimethyl-2-oxobenzo[2,1-b:3,4-c']dipyrrole-5-sulfonamide) is a potent, systemically active ampa receptor antagonist
- 20 January 1994
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 4 (2) , 371-376
- https://doi.org/10.1016/s0960-894x(01)80147-5
Abstract
No abstract availableThis publication has 14 references indexed in Scilit:
- (3SR,4aRS,6RS,8aRS)-6-[2-(1H-Tetrazol-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonistJournal of Medicinal Chemistry, 1993
- Isatin oximes - A novel series of bioavailable non-NMDA antagonistsBioorganic & Medicinal Chemistry Letters, 1993
- Novel class of amino acid antagonists at non-N-methyl-D-aspartic acid excitatory amino acid receptors. Synthesis, in vitro and in vivo pharmacology, and neuroprotectionJournal of Medicinal Chemistry, 1991
- Molecular Cloning and Functional Expression of Glutamate Receptor Subunit GenesScience, 1990
- A Family of AMPA-Selective Glutamate ReceptorsScience, 1990
- 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral IschemiaScience, 1990
- Cloning by functional expression of a member of the glutamate receptor familyNature, 1989
- Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI 52466European Journal of Pharmacology, 1989
- Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor AntagonistsScience, 1988
- The Chemistry of Isatin.Chemical Reviews, 1944