ISOLATION OF CYTOPATHIC AND NONCYTOPATHIC BOVINE VIRAL DIARRHEA VIRUS FROM THE SPLEEN OF CATTLE ACUTELY AND CHRONICALLY AFFECTED WITH BOVINE VIRAL DIARRHEA

  • 1 January 1985
    • journal article
    • research article
    • Vol. 186  (6) , 568-569
Abstract
Both cytopathic and noncytopathic bovine viral diarrhea virus (BVDV) were isolated from 16 of 17 bovine spleens representing 11 herds that had experienced acute BVD and from 12 of 21 bovine spleens from 1 herd affected with chronic BVD. Isolation of cytopathic and noncytopathic BVDV from the same spleen probably indicates that an animal with a persistent, noncytopathic BVDV infection was superinfected with a cytopathic BVDV. The prevalence (> 70%) of 2 viruses in the spleen of cattle with acute or chronic BVD suggested that persistent infection with noncytopathic BVDV may be an important factor in the pathogenesis of BVD.