Salvinorins D−F, New Neoclerodane Diterpenoids from Salvia divinorum, and an Improved Method for the Isolation of Salvinorin A
- 18 April 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 66 (5) , 703-705
- https://doi.org/10.1021/np0205699
Abstract
Three new neoclerodane diterpenoids, salvinorins D-F (4-6), have been isolated from the leaves of Salvia divinorum. The structures were elucidated by chemical and spectroscopic methods, particularly 1D and 2D NMR. A simplified isolation method using chromatography on activated carbon also gave improved yields of the controlled substance salvinorin A (1) and of salvinorin C (3).Keywords
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