Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

This publication has 53 references indexed in Scilit:

• Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas
  Blood, 2007
• CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms
  Blood, 2007
• Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
  BMC Cancer, 2007
• The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
  Nature Cell Biology, 2007
• Regulation of neddylation and deneddylation of cullin1 in SCF ^Skp2 ubiquitin ligase by F-box protein and substrate
  Proceedings of the National Academy of Sciences, 2006
• The role of autophagy in cancer development and response to therapy
  Nature Reviews Cancer, 2005
• Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma
  New England Journal of Medicine, 2005
• Regulation of the cell cycle by SCF-type ubiquitin ligases
  Seminars in Cell & Developmental Biology, 2005
• The HMG-CoA reductase inhibitor simvastatin overcomes cell adhesion–mediated drug resistance in multiple myeloma by geranylgeranylation of Rho protein and activation of Rho kinase
  Blood, 2004
• Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex
  Nature, 2002