Dynamic Ventilation 3He-Magnetic Resonance Imaging With Lung Motion Correction
- 1 March 2002
- journal article
- Published by Wolters Kluwer Health in Investigative Radiology
- Vol. 37 (3) , 126-134
- https://doi.org/10.1097/00004424-200203000-00005
Abstract
Software was developed to correct for lung motion to improve the description of hyperpolarized (3)He gas distribution in the lung. Five volunteers were studied by dynamic ventilation (3)He-MRI using an ultrafast FLASH 2D sequence with a temporal resolution of 128 milliseconds. Signal kinetics were evaluated in the trachea and seven parenchymal Regions of Interest. Reference ranges for healthy subjects were defined for motion-corrected and uncorrected images. Motion correction was successfully performed. Reference ranges were 0.11-1.21 seconds for tracheal transit time, 0-0.02 seconds for trachea-alveolar interval, 0.22-0.62 seconds for alveolar rise time and 0-76.6 arbitrary units for alveolar amplitude for motion corrected images, and 0-1.09 seconds, 0-0.11 seconds, 0.26-0.85 seconds, 46.4-99.8 arbitrary units for uncorrected images. Evaluation of (3)He-distribution in the lung using motion correction of dynamic (3)He-ventilation imaging is feasible and gives more narrow reference ranges.Keywords
This publication has 27 references indexed in Scilit:
- Mechanical Delivery of Aerosolized Gadolinium-DTPA for Pulmonary Ventilation Assessment in MR ImagingInvestigative Radiology, 2001
- Volumetry of Ventilated Airspaces by 3He MRIInvestigative Radiology, 2001
- Radiologische Untersuchungen der Lungenventilation mittels MagnetresonanztomographieRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2000
- Ultraschnelle MRT der Lungenventilation mittels hochpolarisiertem Helium-3*RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2000
- Quantification of Regional Intrapulmonary Oxygen Partial Pressure Evolution during Apnea by 3He MRIJournal of Magnetic Resonance, 1999
- MRI of the pulmonary parenchymaEuropean Radiology, 1999
- Hyperpolarized 3He-enhanced MR imaging of lung transplant recipients: preliminary results.American Journal of Roentgenology, 1999
- Helium-3-MRT der Lungenventilation: Erste klinische AnwendungenRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 1997
- Bronchiolitis Obliterans in Single-Lung Transplant RecipientsChest, 1995
- Polarization ofGas by Optical PumpingPhysical Review B, 1963